The index fell 38.49 points, marking its fourth straight session of losses. It saw a 77.88-point drop in the previous session.
Trading on the main bourse, the Ho Chi Minh Stock Exchange, increased by 28% to VND32.402 trillion (US$1.25 billion).
The VN-30 basket, comprising the 30 largest capped stocks, saw 23 tickers fell, with 7 of them hitting floor price.
Other tickers with large decreases were CTG of state-owned lender VietinBank, down 6.11%, and HDB of HDBank with a 5.94% drop.
Seven blue chips gained, with SAB of brewer Sabeco seeing the biggest jump of 3.5%.
VIC of private conglomerate Vingroup went up 3.4% and VHM of property giant Vinhomes closed 3.2% higher.
Foreign investors were net buyers to the tune of VND254 billion, mainly buying FPT of tech giant FPT Corporation and MWG of electronics retail chain Mobile World.
The HNX-Index for stocks on the Hanoi Stock Exchange, home to mid and small caps, fell 4.21%, while the UPCoM-Index for the Unlisted Public Companies Market went down 0.09%.