The number of active cases is 45, with 223 other patients being discharged, the Ministry of Health said.
Seven people were discharged Wednesday, six in Hanoi and one in the southern province of Tay Ninh. The country has recorded no new cases in the last six days.
Of the remaining patients, 21 have tested negative at least once for the virus.
"Patient 20", a 64-year-old Hanoi woman, has shown health improvement, being able to digest food and no longer having fever.
"Patient 91", a 43-year-old British pilot of Vietnam Airlines being treated in Ho Chi Minh City, also has no fever and no longer requires dialysis.
Over 67,000 people are in isolation, 18,358 of them in hospitals or quarantines, and the rest at home.
The pandemic has spread to 210 countries and territories and the death toll has crossed 177,600.