The index closed 0.48 points lower after dropping 6.25 points in the previous session.
Trading on the Ho Chi Minh Stock Exchange decreased by 2% to VND27.508 trillion (US$1.112 billion).
The VN-30 basket, comprising the 30 largest capped stocks, saw 13 tickers gained.
GVR of Vietnam Rubber Group surged 5.5%, while VIB of private lender VIB went up 3.7% and GAS of state-owned Petrovietnam Gas increased by 1.6%
Ten blue chips fell. VIC of private conglomerate Vingroup slid 3.4%, POW of electricity producer Petrovietnam Power Corporation and BVH of insurance firm Bao Viet Holdings both decreased by 1.3%.
Foreign investors were net seller to the tune of VND1312 billion, mainly selling FRT of electronics retailer FPT Retail and HPG of steelmaker Hoa Phat Group.
The HNX-Index for stocks on the Hanoi Stock Exchange, home to mid and small caps, fell 0.06%, while the UPCoM-Index for the Unlisted Public Companies Market went down 0.31%.