Ho Chi Minh City led with 4,237 new cases, followed by Binh Duong (2,877) and Dong Nai (939).
Saturday's infection tally pushed the infection tally in the ongoing wave since late April to 672,593.
220 deaths were recorded on Saturday, including 165 in HCMC, 39 in its neighbor Binh Duong and seven in the Mekong Delta's Kien Giang.
Other deaths were recorded in Tay Ninh (three), Dong Thap (two) and Binh Thuan, Thanh Hoa, Quang Ngai and Hanoi (one each).
The national death rate over the past week has been 250 a day on average. The coronavirus death toll in Vietnam so far is 16,857, or 2.5 percent of all infections, compared to the world's average of 2.1 percent.
Also on Saturday, 14,903 Covid-19 patients were announced recovered, bringing the total tally of recovered cases so far to 448,368.
The country has vaccinated over 33 million people with at least one Covid-19 vaccine shot. Over 6.3 million have been fully vaccinated.
Ho Chi Minh City, epicenter of the fourth coronavirus wave that hit the country since late April, eased some social distancing rules that had been in place for weeks starting from Thursday, including resumption of business and production at industrial parks of Districts 7, Cu Chi and Can Tho, considered with low Covid risk.
Hanoi allowed food and beverage establishments to resume operation but only takeaway services from Thursday while Da Nang has also allowed people in "medium risk" areas to go out and directly buy goods.
"Medicine package for Covid-19 patients" campaign aims to support patients self-isolating at home. Each donation worth VND380,000 ($16.65) can help buy medicine for one patient. For more information regarding donation methods, kindly refer to this link.