The index closed 6.44 points higher after gaining 8.49 points on Monday.
Trading on the Ho Chi Minh Stock Exchange (HoSE) increased by 14.22% to VND17.44 trillion ($742.16 million).
The VN-30 basket, comprising the 30 largest capped stocks, saw 16 tickers gain.
NVL of property developer Novaland Group led with a 6.8% increase, followed by VHM of property giant Vinhomes, up 2.3%.
HPG of steelmaker Hoa Phat Group went up 2% and BID of state-owned lender BIDV closed 1.6% higher.
Ten blue chips fell.
TPB of private TPBank fell 1.4% and BCM of Becamex Investment and Industrial Development lost 0.7%.
Foreign investors were net buyers to the tune of VND177.19 billion, mainly buying HPG and MSN of conglomerate Masan Group.
The HNX-Index at the Hanoi Stock Exchange, where mid and small caps list, was up 0.38% while the UPCoM-Index at the Unlisted Public Companies Market was up by 0.56%.