The index closed 26.1 points higher after losing 8.3 points on Tuesday.
Trading on the Ho Chi Minh Stock Exchange (HoSE) fell by 21.9% to VND9.41 trillion ($394.22 million).
The VN-30 basket, comprising the 30 largest capped stocks, saw 27 tickers gain.
VHM of property giant Vinhomes rose 6.3%, and CTG of state-owned lender VietinBank gained 6%.
Other gainers included VIC of biggest private conglomerate Vingroup, up 5.3%, KDH of real estate firm Khang Dien House, up 5.2%, and BVH of insurance company Bao Viet Holdings, up 5%.
ACB of Asia Commercial Bank was the only blue chip that fell by 1%.
Foreign investors were net buyers to the tune of VND225.46 billion, mainly buying VHM and CTG.
The HNX-Index at the Hanoi Stock Exchange, where mid and small caps list, was up 2.76% while the UPCoM-Index at the Unlisted Public Companies Market was up by 1.71%.