Two captive bears were sent to the center on Tuesday as the center's first residents.
The two bears were held captive by a family in Hanoi's Phuc Tho District for almost 20 years.
According to Hanoi's Forest Protection Department, 116 bears still live in captivity in Phuc Tho District, and authorities will continue to persuade their owners to turn them in.
In most cases, local residents keep bears to extract their bile for health purposes and for sale.
Since 2006, Animals Asia has rescued 267 captive bears in Vietnam. The bears currently live at Bear Rescue Center Vietnam's first facility in Tam Dao National Park in the northern Vinh Phuc Province.