It will leave Hanoi's Noi Bai Airport at 5:50 p.m.
To book a seat, people have to register with the Indian embassy, which said a ticket costs $370.
On arrival in India, passengers will have to abide by the decision of the appropriate government authority to undergo home quarantine or self-monitoring of their health for 14 days, or as warranted.
Last year India organized dozens of flights to repatriate its citizens stranded in Vietnam.
Vietnam suspended all international flights in March last year and a large number of foreigners remain in the country.
It has been grappling with a new coronavirus wave that began in late April, and there have been nearly 814,000 cases.