The Asiana Airlines flight that landed at Tan Son Nhat Airport on Tuesday night carried 67 passengers.
62 Chinese holding business visas and two Vietnamese citizens were allowed to leave after police found none of them came from China's Hubei Province, the center of the novel coronavirus epidemic, and their health conditions were determined to be normal.
Three other Chinese carrying tourist visas were refused entry.
The International Health Quarantine Center of HCMC has strictly advised the 64 to isolate themselves at home for 14 days, the maximum incubation period of the virus.
13 of them are staying in HCMC while 51 others have traveled to other localities, whose authorities have been informed of their conditions.
Since Vietnam suspended all flights to and from coronavirus-hit areas in China on February 1, 40 flights a day on average have been canceled from Tan Son Nhat airport.
The airport so far has quarantined three persons suspected of being infected with the nCoV. Two of them have tested negative and results are awaited for the third.
Vietnam has so far confirmed 13 nCoV infections, including three in HCMC. Three have recovered and been discharged from hospitals.
Vietnam declared the outbreak an epidemic last Saturday.
The global death toll has reached 724, with 722 dying in mainland China, one each in the Philippines and Hong Kong.