The index closed 4.94 points higher after gaining 5.18 points on Tuesday.
Trading on the Ho Chi Minh Stock Exchange (HoSE) fell by 10.85% to VND17.95 trillion ($758.15 million).
The VN-30 basket, comprising the 30 largest capped stocks, saw 17 tickers gain.
NVL of property developer Novaland Group led with a 6.2% surge, followed by POW of electricity producer Petrovietnam Power Corporation, and SAB of brewer Sabeco, both went up 2.3%.
MWG of electronics retail chain Mobile World fell 1.9% and TPB of private TPBank closed 1.1% lower.
Foreign investors were net buyers to the tune of VND401.39 billion, mainly buying HPG of steelmaker Hoa Phat Group and VHM of property giant Vinhomes.
The HNX-Index at the Hanoi Stock Exchange, where mid and small caps list, was down 0.31% while the UPCoM-Index at the Unlisted Public Companies Market was up by 0.02%.