The index closed 3.07 points higher after gaining 11.22 points on Monday.
Trading on the Ho Chi Minh Stock Exchange (HoSE) increased by 19.12% to VND16.42 trillion ($699 million).
The VN-30 basket, comprising the 30 largest capped stocks, saw 13 tickers gain.
PDR of Phat Dat Real Estate Development led with a 5.8% surge, followed by NVL of property developer Novaland Group, up 2.3%.
MWG of electronics retail chain Mobile World gained 1.8% and MSN of conglomerate Masan Group went up 1.7%.
Ten blue chips fell. VHM of property giant Vinhomes closed 1.1% lower and GAS of state-owned Petrovietnam Gas lost 1%.
Foreign investors were net sellers to the tune of VND503.95 billion, mainly selling EIB of private lender Eximbank and VNM of dairy giant Vinamilk.
The HNX-Index at the Hanoi Stock Exchange, where mid and small caps list, was up 0.46% while the UPCoM-Index at the Unlisted Public Companies Market was up by 0.67%.