The index closed 9.02 points higher after gaining 9.80 points on January 19, the last session before Tet holidays.
Trading on the Ho Chi Minh Stock Exchange (HoSE) fell by 5.35% to VND11.10 trillion ($472.99 million).
The VN-30 basket, comprising the 30 largest capped stocks, saw 20 tickers gain.
SAB of brewer Sabeco led with a 4% rise, followed by GAS of state-owned Petrovietnam Gas, up 3.5%.
GVR of Vietnam Rubber Group rose 3.4% and VIC of private conglomerate Vingroup gained 3.1%.
Eight blue chips fell, with PDR of Phat Dat Real Estate Development losing 3.2%.
BID of state-owned lender BIDV dropped 3% and CTG of state-owned lender VietinBank dipped 2.4%.
Foreign investors were net buyers to the tune of VND518.88 billion, mainly buying HPG of steelmaker Hoa Phat Group and VIC.
The HNX-Index at the Hanoi Stock Exchange, where mid and small caps list, was up 0.40% while the UPCoM-Index at the Unlisted Public Companies Market was up by 1.37%.