The index closed 2.98 points higher after gaining 15.38 points on Tuesday.
Trading on the Ho Chi Minh Stock Exchange (HoSE) increased by 3.72% to VND13.73 trillion ($582.89 million).
The VN-30 basket, comprising the 30 largest capped stocks, saw 13 tickers gained.
GVR of Vietnam Rubber Group led with a 3.3% rise, followed by STB of Ho Chi Minh City-based lender Sacombank, up 3.1%, and GAS of state-owned Petrovietnam Gas, up 1.8%.
Other gainers included NVL of property developer Novaland Group, up 1.6%, and HPG of steelmaker Hoa Phat Group, up 1.1%.
Thirteen blue chips fell, with PDR of Phat Dat Real Estate Development losing 3.2% and SSI of leading brokerage SSI Securities Corporation falling 1.5%.
Foreign investors were net buyers to the tune of VND27.29 billion, mainly buying VHM of property giant Vinhomes and NVL.
The HNX-Index at the Hanoi Stock Exchange, where mid and small caps list, was down 0.18% while the UPCoM-Index at the Unlisted Public Companies Market was up by 0.38%.