The index closed 5.81 points higher after gaining 0.58 points on Monday.
Trading on the Ho Chi Minh Stock Exchange (HoSE) fell by 6% to VND10.74 trillion ($431.95 million).
The VN-30 basket, comprising the 30 largest capped stocks, saw 17 tickers gain.
VRE of retail real estate arm Vincom Retail surged 6.7%, followed by TPB of private TPBank with a 5.3% rise.
VPB of private lender VPBank gained 5.2%, and STB of Ho Chi Minh City-based lender Sacombank went up 4.6%.
Other gainers included STB of Ho Chi Minh City-based lender Sacombank , TCB of the largest private lender Techcombank and SSI of leading brokerage SSI Securities Corporation.
Nine blue chips fell, with HPG of steelmaker Hoa Phat Group losing 4.2%.
Other decliners were PDR of Phat Dat Real Estate Development, down 3%, and MWG of electronics retail chain Mobile World, down 2.9%.
Foreign investors were net sellers to the tune of VND764.84 billion, mainly selling HPG and KBC of industrial real estate developer Kinh Bac City.
The HNX-Index at the Hanoi Stock Exchange, where mid and small caps list, was up 0.92% while the UPCoM-Index at the Unlisted Public Companies Market was up by 0.26%.