The index closed nearly seven points higher after losing over one point Tuesday. It has risen nearly 59 points in the last 10 sessions.
Trading on the Ho Chi Minh Stock Exchange (HoSE) fell marginally to VND16.05 trillion ($691.78 million).
The VN-30 basket, comprising the 30 largest capped stocks, saw 14 tickers gaining.
POW of electricity producer Petrovietnam Power Corporation rose 3 percent to a near four-week high.
GAS of state-owned Petrovietnam Gas gained 2.8 percent, and MSN of conglomerate Masan Group rose 2.3 percent.
Other gainers included PNJ of Phu Nhuan Jewelry, up 2.1 percent, and VCB of state-owned lender Vietcombank, up 2 percent.
Fifteen tickers dropped, with ACB of Asia Commercial Bank losing 1.4 percent and TPB of private TPBank falling 1.1 percent.
Foreign investors were net buyers for the fourth straight session to the tune of VND598 billion, mainly buying DGC of Duc Giang Chemicals Group and VHM of real estate giant Vinhomes.
The HNX-Index at the Hanoi Stock Exchange, where mid and small caps list, was down 0.12 percent while the UPCoM-Index at the Unlisted Public Companies Market was down by 0.37 percent.