The index closed nearly 14 points lower after losing five points Thursday. It is now 44 points lower than the end of last week.
Trading on the Ho Chi Minh Stock Exchange (HoSE), on which the index is based, rose 17 percent to VND21.66 trillion ($945.95 million).
The VN30 basket, comprising the 30 largest capped stocks, saw 22 tickers in the red, with POW of electricity producer Petrovietnam Power Corporation falling 5.5 percent to a four-month low.
SSI of leading brokerage SSI Securities Corporation dropped 4.8 percent to the lowest since the end of October.
TPB of private TPBank lost 4.4 percent while HDB of HDBank fell 3.7 percent.
Seven blue chips gained, with BVH of insurance company Bao Viet Holdings surging 6.9 percent to hit ceiling price.
It is now highest since January 15 last year.
GVR of Vietnam Rubber Group rose 4.2 percent, while GAS of state-owned Petrovietnam Gas gained 3.1 percent
Foreign investors were net buyers to the tune of VND97 billion, mainly buying VPB of private lender VPBank and CTG of state-owned lender VietinBank.
The HNX-Index for stocks on the Hanoi Stock Exchange, home to mid and small caps, dropped 1.65 percent while the UPCoM-Index for the Unlisted Public Companies Market fell 0.93 percent.