Trading on the Ho Chi Minh Stock Exchange (HoSE) increased by 5.51% to VND13.4 trillion ($569 million).
The VN-30 basket, comprising the 30 largest capped stocks, saw 21 tickers dropped.
MWG of electronics retail chain Mobile World fell 2%.
VIB of Vietnam International Commercial Bank lost 1.8%, and VCB of state-owned lender Vietcombank dropped 1.7%.
Other losers were VPB of private lender VPBank, down 1.6%, and BID of state-owned lender BIDV, down 1.3%.
Six blue chips gained, led by HPG of steelmaker Hoa Phat Group with a 3.9% rise.
VNM of dairy giant Vinamilk rose 2.6%, and BVH of insurance company Bao Viet Holdings gained 1.9%.
Foreign investors were net sellers to the tune of VND402.35 billion, mainly selling NVL of real estate developer Novaland Group and VCB.
The HNX-Index at the Hanoi Stock Exchange, where mid and small caps list, was up 0.31% while the UPCoM-Index at the Unlisted Public Companies Market was down by 0.71%.