The index closed 2.04 points higher after gaining the same points on Tuesday.
Trading on the Ho Chi Minh Stock Exchange (HoSE) fell by 25.93% to VND8.30 trillion ($353.37 million).
The VN-30 basket, comprising the 30 largest capped stocks, saw 14 tickers unchanged.
MBB of lender MB went up 1.7%, followed by TCB of the largest private lender Techcombank with a 1.6% rise.
MSN of conglomerate Masan Group gained 1.5% and SSI of leading brokerage SSI Securities Corporation closed 1.2% higher.
Fourteen blue chips dropped, led by MWG of electronics retail chain Mobile World with a 1% decline.
Foreign investors were net sellers to the tune of VND208.91 billion, mainly selling STB of Ho Chi Minh City-based lender Sacombank and VPB of private lender VPBank.
The HNX-Index at the Hanoi Stock Exchange, where mid and small caps list, was down 0.08% while the UPCoM-Index at the Unlisted Public Companies Market was up by 1.52%.