The index closed 2.27 points higher after losing 1.2 points in the previous session.
Trading on the Ho Chi Minh Stock Exchange increased by 22.9% to VND16.861 trillion (US$662.3 million).
The VN-30 basket, comprising the 30 largest capped stocks, saw 13 tickers gained.
HDB of lender HDBank went up 3.3%, CTG of state-owned lender VietinBank grew 1.6%, and VIB of Vietnam International Commercial Bank rose 1.5%.
Ten blue chips fell. POW of electricity producer Petrovietnam Power Corporation slid 1.2%, VHM of property giant Vinhomes dropped 0.7%, and GVR of Vietnam Rubber Group closed 0.6% lower.
Foreign investors were net buyers to the tune of VND615 billion, mainly buying STB of lender Sacombank and CTG.
The HNX-Index for stocks on the Hanoi Stock Exchange, home to mid and small caps, fell 0.33%, while the UPCoM-Index for the Unlisted Public Companies Market went up 0.06%.
MSCI's broad global share index traded flat on Friday to remain 1.6% higher for the week, with Wall Street's S&P 500 on course for a 1.8% weekly gain, Reuters reported.
MSCI's broadest index of Asia-Pacific shares outside Japan was heading for a 1.5% weekly rise and Tokyo's Nikkei closed the week 2% higher.
European stocks lagged, with the Stoxx 600 flat on Friday and 0.3% higher this week.
Analysts said stock markets could change direction as investors returned from holiday and reassessed the risks of elevated U.S. inflation under Trump for richly-valued Wall Street equities.