The game is played at Al-Maktoum Stadium in Dubai, UAE.
Vietnam are topping group G with 11 points after five unbeaten games. The team will need seven points more to secure a place in the final qualification round of World Cup 2022.
Indonesia played six games, but lost five and drew one. They are sitting at the bottom of the group and were out of chances to advance to the next round.
Two teams have faced each other 24 times. Vietnam won six times, drew nine and lost nine. The Golden Dragons are 92nd on world ranking while Indonesia are 173rd.
Vietnam's line up: Bui Tan Truong (goalkeeper), Vu Van Thanh, Do Duy Manh, Que Ngoc Hai, Bui Tien Dung, Nguyen Phong Hong Duy, Nguyen Van Toan, Nguyen Tuan Anh, Nguyen Quang Hai, Phan Van Duc, Nguyen Tien Linh.
Indonesia's line up: Nadeo, Asnawi, Arif, Rizky, Pratama, Rachmat, Syahrian, Yakob, Evan Dimas, Osvaldo.