The new patients were recorded in 43 localities and HCMC continues to account for most.
The southern metropolis recorded 4,627 cases, marking the city's highest daily infection tally since August 1, followed by its neighbor provinces of Binh Duong with 3,628, Dong Nai with 799 and Long An 393.
Of all the local infections recorded Tuesday, 6,780 were detected in the community, up 759 compared to Monday, and the rest in quarantine zones and areas under lockdown.
Among the patients recorded so far in the latest wave, which hit Vietnam in late April, 162,279 have recovered and 8,979 have died.
The deatth toll rose by 348 cases on Tuesday, including 292 in HCMC.
The nation has vaccinated more than 17.64 million of its 96-million population against the coronavirus, and more than 1.92 have gotten two doses.