Ho Chi Minh City and its neighboring provinces of Binh Duong and Dong Nai account for most cases, at 1,140; 521; and 499 respectively.
The ministry also confirmed 54 Covid-19 deaths Wednesday, including 32 in HCMC and eight in Binh Duong, raising the nation's death toll since the start of the pandemic to 21,856, a mortality rate of 2.5 percent.
So far in the fourth wave that emerged six months ago, 895,793 cases have been confirmed and 809,497 have recovered.
Until now, 22.2 million of the nation's 96 million have been fully vaccinated with two doses.