HCMC led with 1,960 cases, followed by Binh Duong, 852, and Dong Nai, 534.
Hanoi recorded nine new cases.
Vietnam has recorded 822,687 Covid-19 cases since the beginning of the pandemic.
119 deaths were recorded Wednesday, bringing the national tally to 20,098.
The number of recoveries was 10,033, bringing the national tally to 757,086.
There are 5,743 patients in severe conditions.
Vietnam has given over 48 million vaccine doses, in which 12 million were second.