The AstraZeneca vaccine has an efficacy rate of 69.2 percent 22 days after the first shot and 80 percent 12 weeks after the second, according to the Ministry of Health.
The ministry has also approved the use of the Pfizer vaccine for the second shot following a first shot of AstraZeneca.
Ho Chi Minh City is in a hurry to vaccinate its population against the coronavirus.
The southern metropolis, which has had 362,493 cases since the fourth wave of infections began in late April, has vaccinated around 6.8 million people at least once.
Around 2.2 million people, or over 31 percent of the adult population, are fully vaccinated.