The index closed 2.30 points higher after gaining 2.65 points on Monday.
Trading on the Ho Chi Minh Stock Exchange (HoSE) fell by 27.94% to VND14.68 trillion ($623.68 million).
The VN-30 basket, comprising the 30 largest capped stocks, saw 12 tickers rise.
SSI of leading brokerage SSI Securities Corporation gained 3.1%, followed by VRE of retail real estate arm Vincom Retail with a 2.8% increase.
HPG of steelmaker Hoa Phat Group went up 2.4% and FPT of IT giant FPT Corporation closed 1.7% higher.
Thirteen blue chips dropped.
PDR of Phat Dat Real Estate Development closed 1.4% lower and TCB of the largest private lender Techcombank lost 1.1%.
Foreign investors were net sellers to the tune of VND457 billion, mainly selling VHM of property giant Vinhomes and STB of Ho Chi Minh City-based lender Sacombank.
The HNX-Index at the Hanoi Stock Exchange, where mid and small caps list, was down 0.08% while the UPCoM-Index at the Unlisted Public Companies Market was up by 0.06%.