The index closed 16.26 points higher after gaining 26.47 points on Tuesday. It has gained over 100 points since November 24.
Trading on the Ho Chi Minh Stock Exchange (HoSE) fell by 2.67% to VND17.76 trillion ($720.49 million).
The VN-30 basket, comprising the 30 largest capped stocks, saw 25 tickers gain.
NVL of real estate developer Novaland Group surged 6.9%, closing at ceiling price for the third session in a row.
It was followed by VIB of Vietnam International Commercial Bank , KDH of real estate firm Khang Dien House and PDR of Phat Dat Real Estate Development, all closed at ceiling price.
Other gainers included HPG of steelmaker Hoa Phat Group, up 5.7%, and VPB of private lender VPBank, up 4%.
Five blue chips fell, with GAS of state-owned Petrovietnam Gas losing 1.6%.
Foreign investors were net buyers to the tune of VND1.67 trillion in their eight straight net buying session, mainly focusing on HPG and VHM of property giant Vinhomes.
The HNX-Index at the Hanoi Stock Exchange, where mid and small caps list, was up 0.27% while the UPCoM-Index at the Unlisted Public Companies Market was up by 0.70%.