The index closed 5.14 points lower after dropping 21.60 points in the previous session.
Trading on the Ho Chi Minh Stock Exchange decreased by 22% to VND22.990 trillion (US$903.2 million).
The VN-30 basket, comprising the 30 largest capped stocks, saw 20 tickers fell.
MSN of conglomerate Masan Group saw a 2.3% decline, BID of state-owned bank BIDV fell 2.1%, and VIB of private lender VIB closed 2.0% lower.
Eight blue chips gained. SSB of lender SeABank went up 1.8%, followed by POW of electricity producer Petrovietnam Power Corporation with a 1.5% growth and HPG of steelmaker Hoa Phat Group, up 1.2%.
Foreign investors were net seller to the tune of VND790 billion, mainly selling VHM of property giant Vinhomes and HPG of Hoa Phat Group.
The HNX-Index for stocks on the Hanoi Stock Exchange, home to mid and small caps, fell 0.33%, while the UPCoM-Index for the Unlisted Public Companies Market went down 0.01%.